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Table 3 Identified genetic differences in regulatory sequences of eda gene and predicted binding sites for potential upstream regulators

From: Expression variations in ectodysplasin-A gene (eda) may contribute to morphological divergence of scales in haplochromine cichlids

Region

Sequence

Species

TFBS

PWM ID

E-value

eda 3’UTR

A----A

Ab, Sd, Pp, Pf

–

–

–

AAAAATAGCTA

All the others

Mef2

M00941

2.1296e-12

eda 3’UTR

GAATAGATTAAC

Sd, Pp, Pf

–

–

–

GAATATATTAAC

All the others

Tcf1

MA0046.1

2.6516e-06

eda/tnfsf13b Intergenic

ACTTT--GCGAG

Sd

Lef1

M00805

2.4053e-06

ACTTTGACTGCGAG

Pp, Pf

Lef1

M00805

5.1356e-05

ACTTCGACTGCGAG

Ab

–

–

–

ACTTCAACTGCGAG

All the others

–

–

–

  1. PWD ID indicates positional weight matrix ID of a predicted binding site and E-values refer to matching similarity between the predicted motif sequences and the PWD IDs
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BMC Ecology and Evolution

ISSN: 2730-7182

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