Fig. 3
From: Molecular evolution of hatching enzymes and their paralogous genes in vertebrates

Syntenic evolution of HE and C6ast genes in vertebrates. The genomic synteny of the HE (green) and other C6ast (magenta, ancestral C6ast; red, patristacin; blue, nephrosin and pactacin) genes was strongly conserved during the evolution of the vertebrates. HECUB1 and HECUB2 indicate HE genes having a single or two CUB domain structures at the C-terminal side, respectively