Figure 1

Enzymes involved in the detoxification of SAH and synthesis of AI-2 and AI-3. Abbreviations: SAM, S-adenosyl-methionine; SAH, S-adenosyl-homocysteine; SRH, S-ribosyl-homocysteine; DPD, 4,5-dihydroxyl-2,3-pentanedione; Pro-AI-2, Ai-2 precursor; AI-2, autoinducer 2; AI-3, autoinducer 3. The numbers in brackets show the numbers of analyzed organisms that have that enzyme (reciprocal best hit).