Figure 5
From: Duplicated genes evolve slower than singletons despite the initial rate increase
Ortholog identification control. a – The symmetrical best BLAST hits approach may mis-identify orthologs in rare cases where there is an ancient gene duplication followed by differential loss of paralogs. b – The dS distributions before and after removal of human-mouse orthologous pairs with dS > 3 standard deviations from the mean (see Methods).